Pubmed link to lab papers
To access a paper, simply click on its title.
A recent Immunity perspective from Stephanie and a group of leading B cell experts (open access until November):
https://authors.elsevier.com/a/1lpaC_OR%7EyinEI
Hoyt LR, Liu E, Olson EC, Jacobsen DR, Siniscalco ER, Krier-Burris RA, Greenfield KG, McBride CD, Alfajaro MM, Amat JAR, Zhao Z, Xu L, Philip V, Verma A, Fourati S, Senger DL, Zhang L, Bunyavanich S, Glass SE, Coffey RJ, Wilen CB, Williams A, Eisenbarth SC. Cysteinyl leukotrienes stimulate gut absorption of food allergens to promote anaphylaxis in mice. Science. 2025 Aug 7;389(6760):eadp0240. doi: 10.1126/science.adp0240.
Zhang B, Chen S, Yin X, McBride CD, Gertie JA, Yurieva M, Bielecka AA, Hoffmann B, Travis Hinson J, Grassmann J, Xu L, Siniscalco ER, Soldatenko A, Hoyt L, Joseph J, Norton EB, Uthaman G, Palm NW, Liu E, Eisenbarth SC, Williams A. Metabolic fitness of IgA(+) plasma cells in the gut requires DOCK8. Mucosal Immunol. 2023 Dec 28;. doi: 10.1016/j.mucimm.2023.12.001. PubMed PMID: 38159726.
Liu EG, Zhang B, Martin V, Anthonypillai J, Kraft M, Grishin A, Grishina G, Catanzaro JR, Chinthrajah S, Sindher T, Manohar M, Quake AZ, Nadeau K, Burks AW, Kim EH, Kulis MD, Henning AK, Jones SM, Leung DYM, Sicherer SH, Wood RA, Yuan Q, Shreffler W, Sampson H, Shabanova V, Eisenbarth SC. Food-specific immunoglobulin A does not correlate with natural tolerance to peanut or egg allergens. Sci Transl Med. 2022 Nov 16;14(671):eabq0599. doi: 10.1126/scitranslmed.abq0599. Epub 2022 Nov 16. PMID: 36383680; PMCID: PMC10219469.
Uthaya Kumar DB, Motakis E, Yurieva M, Kohar V, Martinek J, Wu TC, Khoury J, Grassmann J, Lu M, Palucka K, Kaminski N, Koff JL, Williams A. Bronchial epithelium epithelial-mesenchymal plasticity forms aberrant basaloid-like cells in vitro. Am J Physiol Lung Cell Mol Physiol. 2022 Jun 1;322(6):L822-L841. doi: 10.1152/ajplung.00254.2021. Epub 2022 Apr 19. PMID: 35438006; PMCID: PMC9142163.
Chen JS, Chow RD, Song E, Mao T, Israelow B, Kamath K, Bozekowski J, Haynes WA, Filler RB, Menasche BL, Wei J, Alfajaro MM, Song W, Peng L, Carter L, Weinstein JS, Gowthaman U, Chen S, Craft J, Shon JC, Iwasaki A, Wilen CB, Eisenbarth SC. High-affinity, neutralizing antibodies to SARS-CoV-2 can be made without T follicular helper cells. Sci Immunol. 2022 Feb 4;7(68):eabl5652. doi: 10.1126/sciimmunol.abl5652. Epub 2022 Feb 4. PMID: 34914544.
Soldatenko A, Hoyt LR, Xu L, Calabro S, Lewis SM, Gallman AE, Hudson KE, Stowell SR, Luckey CJ, Zimring JC, Liu D, Santhanakrishnan M, Hendrickson JE, Eisenbarth SC. Innate and Adaptive Immunity to Transfused Allogeneic RBCs in Mice Requires MyD88. J Immunol. 2022 Feb 15;208(4):991-997. doi: 10.4049/jimmunol.2100784. Epub 2022 Jan 17. PubMed PMID: 35039331; PubMed Central PMCID: PMC10107373.
Eisenbarth SC, Baumjohann D, Craft J, Fazilleau N, Ma CS, Tangye SG, Vinuesa CG, Linterman MA. CD4+ T cells that help B cells - a proposal for uniform nomenclature. Trends Immunol. 2021 Jul 6:S1471-4906(21)00117-4. doi: 10.1016/j.it.2021.06.003. Epub ahead of print. PMID: 34244056.
Zhang, B., Liu, E., Gertie, J. A., Joseph, J., Xu, L., Pinker, E. Y., Waizman, D. A., Catanzaro, J., Hamza, K. H., Lahl, K., Gowthaman, U., & Eisenbarth, S. C. (2020). Divergent T follicular helper cell requirement for IgA and IgE production to peanut during allergic sensitization. Science Immunology, 5(47).
Uthaman Gowthaman, Chen JS, Zhang B, Flynn WF, Lu Y, Song W, Joseph J, Gertie JA, Xu L, Collet MA, Grassmann JDS, Simoneau T, Chiang D, Berin MC, Craft JE, Weinstein JS, Williams A, Eisenbarth SC: Identification of a T follicular helper cell subset that drives anaphylactic IgE. Science. 2019 Aug 30. PMID: 31371561
Krishnaswamy JK, Gowthaman U, Zhang B, Mattsson J, Szeponik L, Liu D, Wu R, White T, Calabro S, Xu L, Collet MA, Yurieva M, Alsén S, Fogelstrand P, Walter A, Heath WR, Mueller SN, Yrlid U, Williams A, Eisenbarth SC: Migratory CD11b+ conventional dendritic cells induce T follicular helper cell-dependent antibody responses. Sci Immunol. 2017 Dec 1. PMID: 29196450
Mowel WK, McCright SJ, Kotzin JJ, Collet MA, Uyar A, Chen X, DeLaney A, Spencer SP, Virtue AT, Yang E, Villarino A, Kurachi M, Dunagin MC, Pritchard GH, Stein J, Hughes C, Fonseca-Pereira D, Veiga-Fernandes H, Raj A, Kambayashi T, Brodsky IE, O'Shea JJ, Wherry EJ, Goff LA, Rinn JL, Williams A, Flavell RA, Henao-Mejia J. Group 1 Innate Lymphoid Cell Lineage Identity Is Determined by a cis-Regulatory Element Marked by a Long Non-coding RNA. Immunity. 2017 Sep 19;47(3):435-449.e8. doi: 10.1016/j.immuni.2017.08.012. PMID: 28930659; PMCID: PMC5761663.
Kotzin JJ, Spencer SP, McCright SJ, Kumar DBU, Collet MA, Mowel WK, Elliott EN, Uyar A, Makiya MA, Dunagin MC, Harman CCD, Virtue AT, Zhu S, Bailis W, Stein J, Hughes C, Raj A, Wherry EJ, Goff LA, Klion AD, Rinn JL, Williams A, Flavell RA, Henao-Mejia J. The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan. Nature. 2016 Sep 8;537(7619):239-243. doi: 10.1038/nature19346. Epub 2016 Aug 15. PMID: 27525555; PMCID: PMC5161578.
Calabro S, Liu D, Gallman A, Nascimento MS, Yu Z, Zhang TT, Chen P, Zhang B, Xu L, Gowthaman U, Krishnaswamy JK, Haberman AM, Williams A, Eisenbarth SC: Differential Intrasplenic Migration of Dendritic Cell Subsets Tailors Adaptive Immunity. Cell Rep. 2016 Aug 30; 2016 Aug 18. PMID: 27545885